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- 內容介紹
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Fundamentals of Osteoporosis
By Robert Marcus, David Feldman, Dorothy Nelson and Clifford J. Rosen
552 pages
Trim Size 8 1/2 X 10 7/8 in
Copyright 2010
Key Features
Presents a concise yet comprehensive source of all the latest basic research related to osteoporosis in one reference work
Experts from all areas of osteoporosis research expose readers to genomic and proteomic analysis, histopathology and imaging, as well cellular and molecular mechanisms relevant to assay development and drug discovery
Clear, concise presentations by bone biologists of the cellular and molecular mechanisms underlying osteoporosis
Readership
Academic, medical, and pharmaceutical researchers in bone biology, endocrinology, and rheumatology; Medical researchers in pediatrics, internal medicine, orthopedics, primary care, geriatrics, obstetrics and gynecology, oncology, and nephrology.
Table of Contents
1) The Bone Organ System: Form and Function
Elise F. Morgan, George L. Barnes, and Thomas A. Einhorn
2) The Nature of Osteoporosis
Robert Marcus and Mary L. Bouxsein
3) Skeletal Heterogeneity and the Purposes of Bone Remodeling
A.M. Parfitt
4) Osteoblast Biology
Jane B. Lian and Gary S. Stein
5) Osteoclast Biology
Harry C. Blair, Scott Simonet, David L. Lacey, and Mone Zaidi
6) Osteocytes
Lynda F. Bonewald
7) The Regulatory Role of Matrix Proteins in Mineralization of Bone
Wei Zhu, Pamela G. Robey, and Adele L. Boskey
8) Development of the Skeleton
Sylvain Provot, Ernestina Schipani, Joy Wu, and Henry Kronenberg
9) Mouse Genetics as a Tool to Study Bone Development and Physiology
Clifford J. Rosen and Wesley G. Beamer
10) Parathyroid Hormone and Parathyroid Hormone-Related Protein
Robert A. Nissenson
11) Vitamin D: Biology, Action, and Clinical Implications
David Feldman, Peter J. Malloy, Aruna V. Krishnan, and Eva Balint
12) Regulation of Bone Cell Function by Estrogens
Barry S. Komm, Boris Cheskis, and Peter V.N. Bodine
13) Androgens and Skeletal Biology: Basic Mechanisms
Kristine M. Wiren
14) Phosphatonins
Peter J. Tebben, Theresa J. Berndt, and Rajiv Kumar
15) Wnt Signaling in Bone
Mark L. Johnson and Robert R. Recker
16) Cytokines and Bone Remodeling
Gregory R. Mundy, Babatunde Oyajobi, Gloria Gutierez, Julie Sterling, Susan Padalecki, Florent Elefterious, and Ming Zhao
17) Skeletal Growth Factors
Ernesto Canalis
18) Intercellular Communication during Bone Remodeling
T. John Martin, Gideon A. Roda
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