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- 內容介紹
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Binding: Hardback
Size: 255 x 179 mm
Pages: 516
Weight: 1.256kg
Figures: 65 line diagrams 15 tables
Description
This revised edition reviews the substantial advances in our understanding of the vital role of growth hormone (GH) in maintaining adult health, and the disorders that result from GH deficiency. The first edition, published in 1996, provided a pioneering overview of the subject, and this new edition provides an even more comprehensive account, fully updated with the latest research, clinical applications, and references. The therapeutic benefits of GH treatment in GH deficiency are thoroughly evaluated, including effects on metabolism, cardiac function, exercise performance, psychosocial aspects, and its role in ageing and gender-specific effects. This compilation by the world’s leading experts covers clinical investigation, diagnosis and treatment issues, and encompasses new knowledge of the control and action of GH secretion. The volume is the most authoritative, comprehensive and detailed account available and will be an essential source of reference for all endocrinologists.
Reviews
‘[They] have assembled an impressive list of contributors, including many experts … This book provides an overview of research on GH replacement therapy in GHDAs.’ Journal of the Royal Society of Medicine
‘The chapter on clinical uses of growth hormone releasing peptides and analogues in adults is a unique perspective that will play a more prominent role in the third edition of this extremely valuable book.’ Roy E. Weiss, Doody’s Health Sciences Book Review Journal
‘A timely, well and clearly written text.’ Zvi Laron, Journal of Pediatric Endocrinology and Metabolism
Chapter Contents
Foreword N. Skakkeback; Part I. Introduction: 1. Physiological regulators of growth hormone secretion M. L. Hartman; 2. Insulin-like Growth Factors (IGF) and their IGF-binding proteins - their use for diagnosis of growth hormone deficiency W. F. Blum; 3. Growth hormone and IGF-I effects on in-vivo substrate metabolism in humans N. Møller; 4. Determination of growth hormone and GHBP in serum S. Fisker and H. Ørskov; Part II. Diagnostic and Clinical Aspects: 5. The syndrome of growth hormone deficiency in adults R. Cuneo, F. Salomon and P. H. Sönkse; 6. The diagnosis of growth hormone deficiency in adults D. M. Hoffman and K. K. Y. Ho; 7. Monitoring of growth hormone replacement therapy A. A. Toogood, S. J. Howell and S. M. Shalet; Part III. Growth Hormone Replacement Therapy in Adults with Growth Hormone Deficiency: 8. The effect of growth hormone on protein metabolism D. L. Russell-Jones and M. Umpleby; 9. Growth hormone deficiency, insulin resistance and glucose metabolism F. L. Hew, M. C. Christopher and F. P. Alford; 10. Growth hormone and body composition J. S. Christiansen and N. Vahl; 11. Effects of growth hormone on fluid homeostasis J. Møller; 12. Growth hormone and cardiac function A. Cittadini, S. Longobardi, S. Fazio and L. Sacià; 13. Growth hormone and cardiovascular risk factors T. Rosen; 14. Growth hormone and exercise performance muscle strength and sweat production in healthy subjects and in adults with growth hormone deficiency A. Juul, K. Main and N. E. Skakkebaek; 15. Growth hormone and bone and mineral metabolism J-M. Kaufman and M. Vandeweghe; 16. Growth hormone and thyroid function and energy expenditure J. O. L. Jørgensen, T. Wolthers and J. Weeke; 17. Growth hormone and psychosocial and central nervous effects J.-O. Johansson, L. Wirén and B.-Å. Bengtsson; 18. Impact of gender and age on growth hormone responsiveness P. Burman and G. Johannsson; Part IV. Growth Hormone, Growth-hormone Releasing Peptides and Ageing: 19. Growth hormone and ageing K. G. O'Connor and M. R. Blackman; 20. Growth hormone releasing substances - basic aspects K. K. McKee, A. D. Howard, S. D. Feighner, S. Pony and R. G. Smith; 21. Clinical uses of growth hormone releasing peptides (GHRPs) and GHPR analogues in adults I. M. Chapman and M. O. Thorner; Index.
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