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Thomas' Hematopoietic Cell Transplantation
Third Edition
Edited By: Karl G Blume, Stanford University, California
Stephen J Forman, City of Hope National Medical Center, California
Frederick Appelbaum, Fred Hutchinson Cancer Research Center, Washington State
Illustrations: 363
Pages: 1600
NEW - the leading book in its field now fully updated and revised!
Click here to access two FREE sample chapters!
An Essential resource for all hematologists, oncologists, pathologists, pediatricians, immunologists and all others interested in this dynamic area of medicine!
Why you should buy this book....
Extensive coverage of subject area - from the scientific basis to the view of the future
Includes all experimental research and clinical application
Combined the knowledge and expertise of over 170 international specialists
Clear structure and layout
Over 500 illustrations, including a colour plate section
Why buy the NEW edition......
New and fully revised to reflect the latest developments in this fast moving field
10 new chapters, covering some of the latest developments - see below for the complete tables of content
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Contents
Scientific Basis for Hematopoietic Cell Transplantation
1 A History of Bone Marrow Transplantation, 3
E. Donnall Thomas
2 Uses and Growth of Hematopoietic Cell Transplantation, 9
Mary M. Horowitz
3 Overview of Hematopoietic Cell Transplantation Immunology, 16
Paul J. Martin
4 Histocompatibility, 31
Eric Mickelson & Effie W. Petersdorf
5 Functional Evolution of the Major Histocompatibility Complex, 43
Lakshmi K. Gaur
6 The Hematopoietic Microenvironment, 53
Claudio Brunstein & Catherine M. Verfaillie
7 Molecular Aspects of Stem Cell Renewal, 62
Peter M. Lansdorp
8 Biology of Hematopoietic Stem and Progenitor Cells, 69
Markus G. Manz, Koichi Akashi & Irving L. Weissman
9 Expansion of Hematopoietic Stem Cells, 96
Colleen Delaney, Robert Andrews & Irwin Bernstein
10 Methods for Gene Transfer: Genetic Manipulation of Hematopoietic Stem Cells, 107
Thomas Moritz & David A. Williams
11 Clinical Trials of Gene Marking and Gene Therapy Using Hematopoietic Stem Cells, 118
Donald B. Kohn & Gay M. Crooks
12 Pharmacological Basis for High-Dose Chemotherapy, 130
James H. Doroshow & Timothy Synold
13 Preparative Regimens and Modification of Regimen-Related Toxicities, 158
William I. Bensinger & Ricardo Spielberger
14 Radiotherapeutic Principles of Hematopoietic Cell Transplantation, 178
Brenda Shank & Richard T. Hoppe
15 Radioimmunotherapy and Hematopoietic Cell Transplantation, 198
Dana C. Matthews & Frederick R. Appelbaum
16 Pharmacology and the Use of Immunosuppressive Agents after Hematopoietic Cell Transplantation, 209
Nelson J. Chao
17 T-Cell Depletion to Prevent Graft-vs.-Host Disease, 221
Robert J. Soiffer
18 Documentation of Engraftment and Characterization of Chimerism Following Hematopoietic Cell Transplantation, 234
Eileen Bryant & Paul J. Martin
19 Antibody Mediated Purging, 244
John G. Gribben
20 Pharmacologic Purging of Bone Marrow, 254
O. Michael Colvin
21 Molecular Inhibition of Gene Expression in Hematopoietic Cells, 258
Joanna B. Opalinska & Alan M. Gewirtz
22 The Detection and Significance of Minimal Residual Disease, 272
Jerald P. Radich & Marilyn L. Slovak
23 Pathology of Hematopoietic Cell Transplantation, 286
George E. Sale, Howard M. Shulman & Robert C. Hackman
24 Mechanisms of Tolerance, 300
Megan Sykes
25 The Experimental Basis for Hematopoietic Cell Transplantation for Autoimmune Diseases, 324
Judith A. Shizuru
26 Murine Models for Graft-vs.-Host Disease, 344
Robert Korngold & Thea M. Friedman
27 The Pathophysiology of Graft-vs.-Host Disease, 353
James L.M. Ferrara & Joseph Antin
28 Graft-versus-Tumor Responses, 369
Alexander Fefer
29 Adoptive Immunotherapy with Antigen-Specific T Cells, 380
Stanley R. Riddell & Philip D. Greenberg
30 Autologous Graft-vs.-Host Disease, 405
Allan D. Hess & Richard J. Jones
31 Biostatistical Methods in Hematopoietic Cell Transplantation, 414
Joyce C. Niland
32 Outcomes Research in Hematopoietic Cell Transplantation, 434
Stephanie J. Lee
Patient-Related Issues in Hematopoietic Cell Transplantation
33 The Evaluation and Counseling of Candidates for Hematopoietic Cell Transplantation, 449
Karl G. Blume & Michael D. Amylon
34 Clinical and Administrative Support for Hematopoietic Cell Transplant Programs, 463
Laura L. Adams & Angela A. Johns
35 Nursing Issues in Hematopoietic Cell Transplantation, 469
Rosemary C. Ford, Judy Campbell & Juanita Madison
36 The Patient’s Perspective, 483
Susan K. Stewart
37 Ethical Issues in Hematopoietic Cell Transplantation, 488
David S. Snyder
38 Psychosocial Issues in Hematopoietic Cell Transplantation, 497
Michael A. Andrykowski & Richard P. McQuellon
39 Assessment of Quality of Life in Hematopoietic Cell Transplantation Recipients, 507
Karen Syrjala
40 Sexuality after Hematopoietic Cell Transplantation, 519
D. Kathryn Tierney
Sources of Hematopoietic Cells for Human Transplant
41 Hematopoietic Cell Procurement, Processing and Transplantation: Regulation and Accreditation, 531
Phyllis I. Warkentin, Lewis Nick & Elizabeth J. Shpall
42 Hematopoietic Cell Donors, 538
Dennis L. Confer
43 Cord Blood Hematopoietic Cell Transplantation, 550
Hal E. Broxmeyer & Franklin O. Smith
44 In Utero Transplantation, 565
Alan W. Flake & Esmail D. Zanjani
45 Mobilization of Autologous Peripheral Blood Hematopoietic Cells for Support of High-Dose Cancer Therapy, 576
Judith Ng-Cashin & Thomas Shea
46 Peripheral Blood Hematopoietic Cells for Allogeneic Transplantation, 588
Norbert Schmitz
47 Cryopreservation of Hematopoietic Cells, 599
Scott D. Rowley
48 Recombinant Growth Factors after Hematopoietic Cell Transplantation, 613
Jürgen Finke & Roland Mertelsmann
49 Hematopoietic Cell Donor Registries, 624
Jeffrey W. Chell
Complications and Their Management
50 Graft-vs.-Host Disease, 635
Keith M. Sullivan
51 Bacterial Infections, 665
John R. Wingard & Helen L. Leather
52 Fungal Infections after Hematopoietic Cell Transplantation, 683
Janice (Wes) M. Y. Brown
53 Cytomegalovirus Infection, 701
John A. Zaia
54 Herpes Simplex Virus Infections, 727
James I. Ito
55 Varicella-Zoster Virus Infections, 732
Ann M. Arvin
56 Epstein-Barr Virus Infection, 749
Richard F. Ambinder
57 Other Viral Infections after Hematopoietic Cell Transplantation, 757
Michael Boeckh
58 Gastrointestinal and Hepatic Complications, 769
Simone I. Strasser & George B. McDonald
59 Neurological Complications of Hematopoietic Cell Transplantation, 811
Harry Openshaw
60 Blood Group Incompatibilities and Hemolytic Complications of Hematopoietic Cell Transplantation, 824
Margaret R. O’Donnell
61 Principles of Transfusion Support before and after Hematopoietic Cell Transplantation, 833
Jeffrey McCullough
62 Immunological Reconstitution following Hematopoietic Cell Transplantation, 853
Robertson Parkman & Kenneth I. Weinberg
63 Vaccination of Hematopoietic Cell Transplant Recipients, 862
Clare A. Dykewicz
64 Pulmonary Complications after Hematopoietic Cell Transplantation, 873
David A. Horak
65 Nutritional Support of Hematopoietic Cell Recipients, 883
Sally Weisdorf-Schindele & Sarah Jane Schwarzenberg
66 Pain Management, 894
Jonathan R. Gavrin & F. Peter Buckley
67 Oral Complications, 911
Mark M. Schubert, Douglas E. Peterson & Michele E. Lloid
68 Growth and Development after Hematopoietic Cell Transplantation, 929
Jean E. Sanders
69 Delayed Complications after Hematopoietic Cell Transplantation, 944
Mary E.D. Flowers & H. Joachim Deeg
70 Secondary Malignancies after Hematopoietic Cell Transplantation, 962
Smita Bhatia & Ravi Bhatia
Allogeneic Transplantation for Acquired Diseases
71 Allogeneic Hematopoietic Cell Transplantation for Aplastic Anemia, 981
George E. Georges & Rainer Storb
72 Allogeneic Transplantation for Paroxysmal Nocturnal Hemoglobinuria, 1002
Robert P. Witherspoon
73 Allogeneic Transplantation for Chronic Myeloid Leukemia, 1007
Frederick R. Appelbaum
74 Hematopoietic Cell Transplantation for Juvenile Myelomonocytic Leukemia, 1018
Robert A. Krance
75 Allogeneic Hematopoietic Cell Transplantation for Adult Patients with Acute Myeloid Leukemia, 1025
Keith E. Stockerl-Goldstein & Karl G. Blume
76 Allogeneic Transplantation for Acute Myeloid Leukemia in Children, 1040
David A. Margolis & James T. Casper
77 Allogeneic Hematopoietic Cell Transplantation for Acute Lymphoblastic Leukemia in Adults, 1055
Stephen J. Forman
78 Allogeneic Transplantation for Acute Lymphoblastic Leukemia in Children, 1067
Stella M. Davies, Norma K.C. Ramsay & John H. Kersey
79 Allogeneic Transplantation for Myelodysplastic and Myeloproliferative Disorders, 1084
Jeanne E. Anderson
80 Allogeneic Hematopoietic Cell Transplantation for Multiple Myeloma, 1096
David G. Maloney & Gösta Gahrton
81 Allogeneic Transplantation for Lymphoma and Chronic Lymphocytic Leukemia, 1105
Issa Khouri & Richard Champlin
82 Hematopoietic Cell Transplantation from HLA Partially Matched Related Donors, 1116
Claudio Anasetti & Andrea Velardi
83 Hematopoietic Cell Transplantation from Unrelated Donors, 1132
Effie W. Petersdorf
84 Management of Relapse after Allogeneic Transplantation, 1150
Robert H. Collins, Jr
85 Nonmyeloablative Therapy and Hematopoietic Cell Transplantation for Hematologic Disorders, 1164
Brenda M. Sandmaier & Rainer Storb
86 Allogeneic Hematopoietic Cell Transplantation for Solid Tumors, 1177
Richard W. Childs & Ramaprasad Srinivasan
Autologous Transplantation for Acquired Diseases
87 Autologous and Allogeneic Hematopoietic Cell Transplantation for Hodgkin’s Disease, 1191
Philip J. Bierman & Auayporn Nademanee
88 Autologous Hematopoietic Cell Transplantation for Non-Hodgkin’s Lymphoma, 1207
Sandra J. Horning & James O. Armitage
89 Autologous Hematopoietic Cell Transplantation for Acute Myeloid Leukemia, 1221
Anthony S. Stein & Stephen J. Forman
90 Autologous Hematopoietic Cell Transplantation for Acute Lymphoblastic Leukemia, 1238
Charles A. Linker
91 Autologous Hematopoietic Cell Transplantation for Chronic Myeloid Leukemia, 1250
Ravi Bhatia & Philip B. McGlave
92 Autologous Hematopoietic Cell Transplantation for Multiple Myeloma, 1262
Laurence Catley & Kenneth Anderson
93 Autologous Hematopoietic Cell Transplantation for AL Amyloidosis, 1283
Raymond L. Comenzo & Morie A. Gertz
94 Hematopoietic Cell Transplantation for Breast Cancer, 1298
Karen H. Antman
95 Hematopoietic Cell Transplantation in Germ Cell Tumors, 1308
Brandon Hayes-Lattin & Craig R. Nichols
96 Hematopoietic Cell Transplantation in Ovarian Carcinoma, 1320
Patrick J. Stiff
97 Hematopoietic Cell Transplantation for Neuroblastoma, 1333
Katherine K. Matthay
98 Hematopoietic Cell Transplantation for Brain Tumors, 1345
Ira J. Dunkel & Jonathan L. Finlay
99 Hematopoietic Cell Transplantation for Pediatric Patients with Solid Tumors, 1354
Allen R. Chen & Curt I. Civin
100 AIDS and Hematopoietic Transplantation: HIV Infection, AIDS, Lymphoma and Gene Therapy, 1369
John A. Zaia, J. Scott Cairns & John J. Rossi
101 Hematopoietic Stem Cell Transplantation for Autoimmune Diseases, 1385
Alan Tyndall & Alois Gratwohl
102 Prevention and Therapy of Relapse following Autologous Hematopoietic Cell Transplantation, 1394
Robert S. Negrin
Allogeneic Transplantation for Inherited Disease
103 Marrow Transplantation in Thalassemia, 1409
Guido Lucarelli & Reginald A. Clift
104 Hematopoietic Cell Transplantation for Sickle Cell Disease, 1417
Mark C. Walters
105 Hematopoietic Cell Transplantation for Immunodeficiency Diseases, 1430
Trudy N. Small, Wilhelm Friedrich & Richard J. O’Reilly
106 Hematopoietic Cell Transplantation for Osteopetrosis, 1443
Peter F. Coccia
107 Hematopoietic Cell Transplantation for Storage Diseases, 1455
Charles Peters
108 Hematopoietic Cell Transplantation for Macrophage and Granulocyte Disorders, 1471
Rajni Agarwal
109 Hematopoietic Cell Transplantation for Fanconi Anemia, 1483
John E. Wagner, Margaret L. MacMillan & Arleen D. Auerbach
The Future
110 Hematopoietic Cell Transplantation in the 21st Century, 1507
Ernest Beutler
Colorplates, facing page 296
Robert C. Hackman
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