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- 內容介紹
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Molecular Diagnosis of Cancer
Methods and Protocols, 2nd ed.
Roulston, Joseph E. (University of Edinburgh, Edinburgh, UK)
Bartlett, John M. S. (University of Glasgow, Glasgow, UK)
Binding: Hardcover
Pub. Date: March 2004
Pages: 408
ISBN: 1-58829-160-X
Abstract:
A diverse collection of readily reproducible methods for use in cancer detection. Highlights include FISH-based methodologies currently used in the diagnosis of solid tumors, the molecular diagnosis of genetic abnormalities by DNA array technologies-including sequence-specific oligonucleotide arrays and CGH arrays-and methodologies directed at the detection of epigenetic events and at quantitative gene expression. The authors apply these novel diagnostic procedures to a broad range of cases taken from cytology, solid tumor pathology, hematology, and rare cell detection, paying special attention to potential future developments and the practical problems of dealing with quality control and accuracy.
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