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Middleton's Allergy: Principles and Practice e-dition, 2-Volume Set, 6th Edition - Text with Continually Updated Online Reference By N. Franklin Adkinson, Jr., MD, John W. Yunginger, MD, William W. Busse, MD, Bruce S. Bochner, MD, Stephen T. Holgate, MD, DSc, FRCP, FRCPE and F. Estelle R. Simons, MD, PFCPC
Approx. 1746 pages, Over 500 ills,
Copyright 2004
Description
This new 6th Edition carries on the long-standing tradition of excellence that has earned Middleton's ALLERGY: Principles & Practice a worldwide reputation as the leader in its field. The new edition provides comprehensive coverage of state-of-the-art basic science as well as authoritative guidance on the practical aspects of day-to-day diagnosis and management. By accessing Middleton's Allergy Online, you'll be able to perform rapid electronic searches of the entire contents of the 2-volume set and much, much more!
Key Features
Presents fresh perspectives from 3 new editors and a multitude of new contributors.
Delivers a truly international perspective on every aspect of allergic disease—putting global "best practices" at your fingertips.
Offers brand-new coverage of aerobiology of outdoor allergens • indoor and outdoor air pollution • allergy vaccines • antigen presentation and immunoregulation • and many other topics! You'll also find. . .
Ongoing content updates through the enclosed website.
Many of the illustrations from the 2-volume set in downloadable format.
Links to relevant web sites.
Patient education materials.
And much more!
Table of Contents
Section A: Immunology 1: The Immune System: An Overview 2: Molecular Biology and Genetic Engineering 3: Principles and Application of Genetics 4: Genetics of Allergic Disease and Asthma 5: Immunoglobulin Structure and Function 6: The Complement System 7: Synthesis and Regulation of Immunoglobulin E 8: Signal Transduction 9: Cellular Adhesion in Inflammation 10: Cytokines in Allergic Inflammation 11: Chemokines in Cell Movement and Inflammation 12: Antigen Presentation and Immunoregulation 13: Mast Cell–Derived Mediators 14: Lipid Mediators of Hypersensitivity and Inflammation 15: Neuronal Control of Airway Function in Allergy 16: Biochemical Events in Basophil or Mast Cell Activation and Mediator Release 17: Biology of Lymphocytes 18: Biology and Role of Neutrophils in Asthma 19: Biology of Eosinophils 20: Biology of Mast Cells 21: Biology of Basophils 22: Biology of Monocytes and Macrophages 23: Biology of Epithelial Cells 24: Biology of Endothelial Cells 25: Biology of Airway Smooth Muscle Cells 26: Apoptosis of Inflammatory Cells 27: Delayed-Type Hypersensitivity and Cellular Immunity: Effector/Regulator Molecules and Mechanisms 28: Allergic Inflammation: Initiation, Progression, and Resolution 29: Animal Models of Asthma 30: Pathophysiology of Allergic Inflammation 31: Immunopathology of Allergic Airway Inflammation
Section B Aerobiology and Diagnosis of Allergy
32: Air Pollution: Indoor and Outdoor 33: Aerobiology Outdoor Allergens 34: Indoor Allergens 35: Preparation and Standardization of Allergen Extracts 36: Allergen Structure and Function 37: Methods in Laboratory Immunology 38: In Vivo Methods for Study of Allergy: Skin Tests, Techniques, and Interpretation 39: Nasal Provocation Testing 40: Bronchial Challenge Testing
Section C Physiology
41: Structural and Functional Cutaneous Immunology 42: Immunologic and Nonimmunologic Lung Defense Mechanisms 43: Structure and Function of Airway Smooth Muscles 44: Development, Structure, and Physiology in Normal and Asthmatic Lung 45: Airway Mucus and the Mucociliary System 46: Aerosols 47: Anatomy and Physiology of the Nose and Control of Nasal Airflow
Section D Pharmacology
48: Principles of Pharmacotherapeutics 49: Beta-Adrenergic Agonists 50: Theophylline and Phosphodiesterase Inhibitors 51: Antihistamines 52:Glucocorticosteroids A) Mechanisms of Action in Allergic Diseases B) Clinical Use 53: The Chromones: Cromolyn Sodium and Nedocromil Sodium 54: Cholinergic Mechanisms and Anticholinergic Therapy in Respiratory Diseases 55: Antileukotriene Therapy in Asthma 56: Immunomodulators
Section E Clinical Science
57: Cell-Mediated Immunity in Health and Disease 58: Immune Complexes and Allergic Disease 59: Primary Immunodeficiency Diseases 60: Approach to the Patient with Recurrent Infections 61: Immunology of HIV Infection and Its Relationship to Allergic Diseases 62: Clinical Significance of IgE 63: Eosinophilia and Easinophil-Related Disorders 64: Epidemiology of Asthma and Allergic Diseases 65: Allergic Disease in Childhood A) Natural History, Development, and Prevention B) Early Childhood Correlates of Allergic Disease 66: Asthma: Definition and of Allergic Disease in Pathogenesis 67: Pathology of Asthma Compared with Chronic Obstructive Pulmonary Disease 68: Asthma in Infancy and Childhood 69: Asthma in Adults: Evaluation and Management 70: Asthma Guidelines and Outcomes 71: Asthma and Allergic Diseases During Pregnancy 72: Exercise-Induced Airway Narrowing 73: Occupational Asthma 74: Allergic Bronchopulmonary Aspergillosis 75: Hypersensitivity Pneumonitis 76: Allergic and Nonallergic Rhinitis 77: Endoscopy of the Upper Airway 78: Nasal Polyps and Sinusitis 79: Otitis Media 80: Immunotherapy for Inhalant Allergens 81: Insect Allergy 82: Natural Rubber Latex Allergy 83: Anaphylaxis and Anaphylactoid Reactions 84: Mastocytosis Syndromes 85: Urticaria and Angioedema 86: Atopic Dermatitis 87: Contact Dermatitis 88: Allergic and Immunologic Disorders of the Eye 89: Adverse Reactions to Foods 90: Adverse Reactions to Food and Drug Additives 91: Adverse Reactions to Vaccines 92: Drug Allergy
Appendix A Chemokines
Appendix BAdhesion Molecules
Appendix C Leukocytes
Appendix D Internet sites
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