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Amyloid Proteins: Methods and Protocols

-基礎醫學科

- 編號： 1588293378

- 作者： Einar M

- 原價-4125 - (熱賣價)3630 - 節省 ↓12%

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- 內容介紹

Amyloid Proteins:Methods and Protocols
Sigurdsson, Einar M. (New York University School of Medicine, New York, NY)
Binding: Hardcover
Pub. Date: December 2004
Pages: 408
ISBN: 1588293378
Abstract:
A proven collection of readily reproducible techniques for studying amyloid proteins and their involvement in the etiology, pathogenesis, diagnosis, and therapy of amyloid diseases. The contributors provide methods for the preparation of amyloid and its precursors (oligomers and protofibrils), in vitro assays and analytical techniques for their study, and cell culture models and assays for the production of amyloid proteins. Additional chapters present readily reproducible techniques for amyloid extraction from tissue, its detection in vitro and in vivo, as well as nontransgenic methods for developing amyloid mouse models. The protocols follow the successful Methods in Molecular Biology™ series format, each offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.