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Transplantation of the Liver, 2nd Edition
By Ronald W. Busuttil, MD, PhD and Goran B. Klintmalm, MD, PhD
Approx. 1520 pages, 650 ills.
Trim size 8 5/16 X 10 7/8 in.
Copyright 2005
Description
Spearheaded by two of the world's preeminent experts in liver surgery, the new edition of this landmark masterwork encompasses all of today's best knowledge in the field. It provides detailed discussions of everything from pathophysiology and patient and donor selection…through transplantation anesthesia and full range of operative procedures…to immunosuppression, postoperative care, and ethical issues. The result is an ideal single source for authoritative, up-to-the-minute guidance on every imaginable aspect of liver transplantation.
With 104 additional contributing experts
Reviews
"[A] magnum opus…A standard textbook and a wonderful reference work on all aspects of liver transplantation…Readers around the world who have an interest in liver grafting will need this book. I recommend it enthusiastically."--NEJM "This superb book will be the most comprehensive and most used reference in the transplantation library."--Hepatology "An ambitious and highly successful work…the standard by which subsequent texts on human liver transplantation will be measured."--Gastroenterology
Key Features
Discusses the background and available management options for each hepatic disease entity.
Addresses anesthesia for liver transplantation„oa crucial aspect of successful surgery that is often neglected in other sources.
Provides step-by-step descriptions of today's full range of transplantation techniques.
Details postoperative care, including intensive
Considers the ethical issues involved in using living donors.
Delivers pearls and pitfalls that provide important advice from world-renowned experts.
New to this Edition
Offers sweeping updates throughout, with contributions from many brand-new authors on the front lines of research and clinical practice. li>Presents the latest information on immunosuppression, focusing on side effects and morbidities associated with the currently available drugs.
Covers hot topics such as adult living donor transplantation, including relevant imaging techniques • liver allocation in the United States and Europe • Hepatitis C • outcomes • management of the necrotic liver • new immunosup¬pres¬sive drugs • the development of a bioartificial liver • and much more.
Table of Contents
I. General Considerations
1. History of Liver and Other Splanchnic Organ Transplantation 2. Liver Organ Allocation: The U.S. Model 3. Liver Organ Allocation: The Great Britain and European Models 4. Hepatic Anatomy 5. Hepatic Physiology and Assessment of Hepatic Function 6. Molecular Biology of the Liver 7. Influence of Liver Transplantation on Liver Surgery
II. Patient Evaluation: Adult
8. Current Indications, Contraindications and Timing for Liver Transplantation 9. Transplantation for Viral Hepatitis A & B 10. Transplantation for Hepatitis C 11. Transplantation for Fulminant Hepatic Failure 12. Transplantation for Primary Biliary Cirrhosis 13. Transplantation for Sclerosing Cholangitis 14. Liver Transplantation for Autoimmune Chronic Active Hepatitis 15. Transplantation for Primary Hepatic Malignancy 16. Liver Transplantation for Metastatic Hepatic Malignancy 17. Liver Transplantation for Hematological Disorders: Hereditary Hemochromatosis, Protophyria, and Coagulation Defects 18. Transplantation for Budd-Chiari Syndrome 19. Liver Transplantation for Alcoholic Cirrhosis 20. Unusual Indications for Liver Transplantation
III. Patient Evaluation: Pediatric
21. General Criteria for Pediatric Transplantation 22. Transplantation for Cholestatic Liver Disease 23. Transplantation for Biliary Atresia 24. Liver Transplantation for Metabolic Disease 25. Transplantation for Hepatic Malignancy in Children 26. Nutritional Aspects of Pediatric Liver Transplantation
IV. Special Considerations in Patient Evaluation
27. Ethical Decisions in Liver Transplantation 28. Psychosocial Assessment of Adult Liver Transplant Recipients 29. Pretransplantation Evaluation: Pulmonary, Cardiac, and Renal 30. Pretransplantation Infectious Disease Screening for Transplantation Candidates 31. Role of the Clinical Nurse Coordinator: Preoperative Care 32. Radiologic Evaluation in the Liver Trnaplant Patient 33. Monitoring and Care of the Patient Prior to Transplantation 34. Nutritional Aspects of Adult Liver Transplantation 35. Surgery for Portal Hypertension in the Era of Liver Transplantation
V. The Operation
36. Donor Selection and Management 37. The Donor Operation 38. Principles of Organ Preservation 39. The Recipient Hepatectomy and Grafting 40. Anesthesia for Liver Transplantation
VI. Split and Living Donor Transplantation
41. Split Liver Transplantation for the Pediatric and Adult Recipient 42. Living Related Liver Transplantation in Pediatric Recipients 43. Split Liver Transplantation for Two Adults 44. Adult Living Donor and Recipient Evaluation and Selection 45. Adult Living Donor Hepatectomy and Recipient Operation 46. Imaging Techniques in Living Donor Transplantation 47. Outcomes in Living Donor Transplantation
VII. Unusual Operative Problems
48. Venous Anomalies Including Protal Vein Thrombosis and Prior Portosystemic Shunts 49. Liver Transplantation and Situs Inversus 50. Retransplantation 51. Clinical Management of Necrotic Liver During Transplantation Surgery 52. Transplantation of the Liver With Digestive Organs 53. Combined Liver-Kidney Transplantation 54. Auxiliary Transplants
VIII. Postoperative Care
55. Postoperative Intensive Care Management 56. Postoperative Intensive Care Management: Children 57. Postoperative Care Management: Adults 58. Postoperative Care Management: Children 59. Renal Failure in the Adult Transplant Recipient 60. Graft Failure: Cause, Etiology, Recognition and Treatment 61. Technical Problems: Biliary 62. Technical Problems: Vascular 63. Infections After Liver Transplantation 64. Late Onset Complications and Recurrent Non-Malignant Disease 65. Neuropsychiatric Outcomes in Liver Transplantation 66. Transplantation of the Liver: Postoperative Neurological Disorders and Prognosis 67. Role of the Posttransplantation Coordinator
IX. Liver Transplant Pathology
68. Histological Patterns of Rejection and Other Causes of Liver Dysfunction 69. Pathology of Recurrence of Non-Neoplastic Disease After Liver Transplantation 70. Posttransplantation De Novo Malignancies
X. Immunology of Liver Transplantation
71. Rejection After Transplantation 72. Cell Migration, Chimerism, and Graft Acceptance, With Particular Reference To the Liver 73. ABO, Tissue Typing, and Crossmatching Incompatibility in Liver Transplantation
XI. Immunosuppression
74. Induction and Maintenance of Immunosuppression 75. Special Considerations for Pediatric Immunosuppression After Liver Transplantation 76. Treatment of Acute and Chronic Rejection 77. New Immunosuppressive Drugs
XII. Survival and Results
78. Preoperative Predictors of Outcome in Liver Transplantation: Models for Defining High-Risk Recipients 79. Overall National Results of Liver Transplantation Between 1987 and 2000 80. Long-Term Functional Recovery and Quality of Life 81. Results: Survival and Quality of Life After Orthotopic Liver Transplantation in Children
XIII. Future Developments in Liver Transplantation
82. Gene Therapy in Transplantation 83. Xenotransplantation 84. Hepatocyte Transplantation 85. New Approaches in Immunosuppression 86. Ischemia Reperfusion Injury of the Liver 87. Extracorporeal Xenogeneic Liver Support 88. Development of Bio Artificial Liver
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