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- 內容介紹
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Viral Hepatitis
Third Edition
Edited By: Howard Thomas,
Stanley Lemon,
Arie Zuckerman,
Hardback
1405130059
276 x 219mm, 8.62 x 10.87in
Illustrations: 550
Pages: 672
2005年
There has been an explosion of both the incidence and medical knowledge of viral hepatitis over the last two decades. The incidence of infection and disease is continuing to increase dramatically. The CDC estimates that 93,000 people in the US were infected with Hepatitis A during 2001 and that 31.3% of the US population have been infected at some point. Similarly, there are now estimated to be 1.25million people in the US who are chronically infected with Hepatitis B, resulting in 5,000 deaths per year. For Hepatitis C, the figures are 2.7 million people infected in the US, resulting in 8,000-10,000 deaths per year.
Not only is the incidence of infection and disease increasing, but new Hepatitis viruses have been discovered, as well as the launch of new pharmaceutical products.
Viral Hepatitis by Zuckerman & Thomas was the first comprehensive book on hepatitis and it is recognised as the standard reference text in this field. It was previously published by Churchill Livingstone (for two editions), but has now joined the Blackwell gastroenterology and hepatology list of books.
The Editors are joined by a North American co-Editor for this edition - Professor Stanley Lemon of the University of Texas, Galveston, TX, USA.
The new third edition is entirely revised and updated to cover the recent advances in diagnosis and treatment.
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Contents
Section 1
1. Liver stem cells in persistent viral infection, liver regeneration and Cancer
2. The role of the liver in the immune response
Section II -
3. Clinical Features of Hepatitis
4. Diagnosis
5. Evolution of hepatitis viruses
Section III - Hepatitis A Virus
6. Structure and Molecular Virology
7. Epidemiology
8. Natural History and Experimental Models
9. Prevention
Section IV - Hepadnaviridae
10. Structure and Molecular Virology
11. Epidemiology of Hepatitis B
12. Avihepadnaviridae
13. Woodchuck Hepadnaviruses
14. Molecular Variants of Hepatitis B Virus - surface antigen
15. Molecular Variants of Hepatitis B Virus - core antigen
16. Natural History of Chronic Hepatitis B and Hepatocellular Carcinoma
17. Hepatocellular Carcinoma: Molecular Aspects in hepatitis B
18. Pathogenesis of Chronic Hepatitis B - animal studies
19. Pathogenesis of Chronic Hepatitis B - human studies
20. Treatment of Chronic Hepatitis B
21. Management of drug resistant variants
22. Liver Transplantation in the Management of Chronic Viral Hepatitis
23. Protection against hepatitis B
SECTION V: Hepatitis C Virus
24. Structure and Molecular Virology
25. Epidemiology
26. Immune response to HCV in acute & chronic infection.
27. Chimpanzee model of HCV.
28. Autoimmune disorders associated with hepatitis C.
29. CNS complication of HCV infection
30. In vitro replication models of HCV
31. Small animal models of Hepatitis C
32. Progression of Hepatitis C
33. Natural History of Chronic Hepatitis C and Hepatocellular Carcinoma
34. Treatment of Chronic Hepatitis C
35. New drugs for management of hepatitis C.
36. Prevention of hepatitis C.
Section VI - Hepatitis D Virus
37. Structure and Molecular Virology
38. Epidemiology Natural History
39. Treatment of Hepatitis D
Section VII - Hepatitis E Virus
40. Structure and Molecular biology.
41. Hepatitis E as a Zoonotic Disease
42. Epidemiology, Natural History and Experimental Models Diagnosis -
43. Prevention.
Section VIII - Clinical Aspects of Viral Liver Disease
44. Etiology of Fulminant Hepatitis.
45. Treatment of Fulminant Hepatitis.
46. Transfusion-Associated Hepatitis.
47. Hepatitis and Hemophila
48. Occupational Aspects of Hepatitis.
49. Neonatal and Pediatric Infection
50. Management of Hepatocellular Carcinoma
51. Application of Molecular Biology to the Diagnosis of Viral Hepatitis
52. Hepatitis in HIV-infected Persons
53. Treatment of extra-hepatic diseases caused by HBV & HCV.
54. The Histologist's Role in Diagnosis and Management of Chronic Hepatitis B & C.
55. Disinfection and Sterilization
56. Mechanisms of interferon resistance.
57. Novel cytokines for all hepatitis.
58. New in vitro testing systems.
59. New vaccine technology (oral vaccines/adjuvants).
60. Safety of hepatitis vaccines.
61. History of hepatitis.
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