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In Search of Madness
Schizophrenia and Neuroscience
R. WALTER HEINRICHS, York University, Canada
This book evaluates the progress of schizophrenia science by summarizing what is known about how patients with the illness differ from healthy people. The tools of meta-analysis are first explained and then employed to make the strength and consistency of these differences explicit. Beginning with the study of symptoms, then moving through the search for objective disease markers, findings on the cognitive functions, structure, physiology, chemistry, and development of the brain, this book is a journey into the enigma of madness and its science. What emerges is an illness that reveals itself most strongly in thought processes, not biology. Schizophrenia is an anomaly at the frontier of mind and brain, but In Search of Madness points the way to its solution.
"This book by Heinrichs is one of the most scholarly treatises by a single author that I have read in the past decade. What makes it unique is that it is written by a research neuropsychologist and that it attempts to integrate a vast array of clinical and research findings regarding the etiology and pathophysiology of schizophrenia. . . . . This book will be a treat for schizophrenia researchers in particular and clinical neuroscience researchers in general. It will serve as an excellent reference for students and trainees in psychiatry, psychology, neurology, and cognitive science. Although intensely evidence based, the book is highly readable and unfolds its content in an intellectually pleasing, systematic approach. . . . [F]or those in search of a coherent and comprehensive understanding of the major modern themes of schizophrenia research, this is a highly worthwhile book to own and to refer to repeatedly." -- Journal of Clinical Psychiatry
PR campaign to national and scientific media Advertising in major psychological and psychiatric journals, as well as Nature and The New York Review of Books
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368 pp.; 15 line illus; 6-1/8 x 9-1/4; 0-19-512219-4
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