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- 內容介紹
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Adenosine Receptors and Parkinson's Disease
by Hiroshi Kase (Editor), Peter J. Richardson (Editor), Peter Jenner (Editor)
Hardcover - 275 pages 1st edition (January 15, 2000)
Academic Pr; ISBN: 0124004059 ; Dimensions (in inches): 0.71 x 9.28 x 6.25
Editorial Reviews
From Book News, Inc.
Offers an overview of adenosine antagonists and Parkinson's disease. Delineates a novel mechanism and concept of adenosine receptor antagonists, explaining groundbreaking research in biochemistry, molecular biology, medicinal chemistry, electrophysiology, pharmacology, and neurochemistry. Discusses the development of a novel non-dopaminomimetic agent for Parkinson's disease, presents a new mechanism of action of adenosine receptor antagonists in motor function, and proposes a hypothesis of adenosine receptor function in the striatum. Kase is involved in pharmaceutical research and development at a Japanese company; Richardson teaches pharmacology at the University of Cambridge; Jenner is affiliated with the Neurodegenerative Diseases Research Center at King's College London.Book News, Inc.®, Portland, OR
Book Description
This book is the first definitive overview on adenosine receptor antagonists and their application to the treatment of Parkinson's Disease. The effect of these novel non-dopamine drugs on vitro and in vivo systems clearly shows their potential for the treatment of this debilitating disease. This book covers how the Parkinson's disease antagonist drug, A2A, has been researched, developed, and tested. It is an essential book for researchers interested in the basal ganglia, purine biology, and... read more
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