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Neurobiology of Disease
Sid Gilman (Editor-in-Chief)
Department of Neurology, University of Michigan, Ann Arbor, MI, USA
ISBN: 978-0-12-088592-3
ISBN10: 0-12-088592-1 Book/Hardback
Line Illustrations: 96
Measurements: 8 1/2 X 11 in
Pages: 1104
Imprint: Academic Press
Publication Date: 2007
Provides cutting edge information about fundamental mechanisms underlying neurological diseases
Amply supplied with tables, illustrations and references
Includes supporting clinical information putting the mechanisms of disease into perspective
Description back to top
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This book is aimed at any basic scientist or clinician scientist teaching a course or conducting research on the basic science underlying the major neurological diseases. It provides an excellent overview of cutting-edge research on the fundamental disorders of the nervous system, including physiological and molecular aspects of dysfunction. The major categories of neurological disease are covered, and the chapters provide specific information about particular diseases exemplifying each of these categories. Sufficient clinical information is included to put into perspective the basic mechanisms discussed. The book assembles a world-class team of section editors and chapters written by acknowledged experts in their respective fields.
Contents back to top
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Part I. Central Nervous System
Section A. Metabolic Diseases – Hugo W. Moser
Chapter 1: Leukodystrophies
Chapter 2: Lysosomal Disorders of the Nervous System
Chapter 3: The Neurobiology of Peroxisomal Disorders
Chapter 4: Creatine Deficiency Syndromes
Section B. Neurodegenerative Disorders – Gregor Wenning
Chapter 5: Parkinson’s Disease
Chapter 6: Alzheimer Disease
Chapter 7: Multiple System Atrophy
Chapter 8: Olivopontocerebellar Atrophy (OPCA)
Chapter 9: Neurobiology of Progressive Supranuclear Palsy
Section C. Genetic Diseases – Christopher Gomez
Chapter 10: Protein Aggregation Disorders
Chapter 11: RNA-Based Disorders of Muscle and Brain
Chapter 12: Ion Channel Disorders
Chapter 13: Spinocerebellar Ataxia Type 1
Chapter 14: Shared Transcriptional Consequences of Mitochondrial Disease, Ischemic Hypoxia and Chemical Hypoxia
Section D. Neuroimmunological Disorders – Anthony T. Reder
Chapter 15: Paraneoplastic Neurological Disorders
Chapter 16: Systemic Lupus Erythematosus: Descriptive Past and Mechanistic Future
Chapter 17: Progressive Multifocal Leukoencephalopathy
Chapter 18: Multiple Sclerosis
Chapter 19: Immune-Mediated Neuropathies
Chapter 20: Hashimoto Encephalopathy
Section E. Cerebrovascular Diseases – Lewis Morgenstern
Chapter 21: Vascular Cognitive Impairment
Chapter 22: Cardioembolism
Chapter 23: Coagulation Disorders
Chapter 24: Clinical and Neurobiological Aspects of Stroke Recovery
Chapter 25: Non-Atherosclerotic Cerebral Vasculopathies
Chapter 26: Subarachnoid Hemorrhage
Chapter 27: Cerebral Ischemia: Molecular Mechanisms and Protective Therapies
Chapter 28: Intracerebral Hemorrhage and Intraventricular Hemorrhage-Induced Brain Injury
Section F. Paroxysmal Disorders – Timothy A. Pedley
Chapter 29: Idiopathic Epilepsies
Chapter 30: Paroxysmal Dyskinesia
Chapter 31: Neurobiology of Myoclonus
Chapter 32: Channelopathies of the Nervous System
Chapter 33: Migraine
Chapter 34: Temporal Lobe Epilepsy
Section G. Neoplastic Diseases – John Laterra
Chapter 35: CNS Metastases
Robert J. Weil
Chapter 36: Meningioma
Katrin Lamszus, Christian Hagel, and Manfred Westphal
Chapter 37: CNS Lymphoma
Corresponding Author: Dr. Batchelor
Chapter 38: Neurofibromatosis 1
Linda Piersall and David H. Gutmann
Chapter 39: Medulloblastoma and Primitive Neuroectodermal Tumors
Said Elshihabi and James T. Rutka
Chapter 40: Glioma
Anders I. Persson, QiWen Fan, Joanna J. Phillips, and William A. Weiss
Section H. Infectious Diseases – Richard T. Johnson
Chapter 41: Bacterial & Fungal
Chapter 42: Parasitic Infections
Chapter 43: Prion Diseases
Chapter 44: Central Nervous System Viral Infections: Clinical Aspects and Pathogenic Mechanisms
Section I. Motor Neuron Diseases – Eva L. Feldman
Chapter 45: Spinal Muscular Atrophy
Chapter 46: Amyotrophic Lateral Sclerosis-Like Syndromes Associated with Malignancy
Chapter 47: Amyotrophic Lateral Sclerosis (ALS): Idiopathic and Inherited
Chapter 48: Hereditary Spastic Paraplegia and Primary Lateral Sclerosis
Chapter 49: Poliomyelitis
Chapter 50: Spinobulbar Muscular Atrophy (Kennedy’s Disease)
Section J. Malformations and Developmental Disorders – Michael V. Johnston
Chapter 51: Neurobiology of Genetic Mental Retardation
Chapter 52: Cerebral Palsy
Chapter 53: Autism
Chapter 54: Neurobiology of Dyslexia
Chapter 55: Neonatal Brain Injuries
Chapter 56: Spina Bifida
Chapter 57: Circuits to Synapses: The Pathophysiology of Tourette Syndrome
Chapter 58: Attention Deficit Hyperactivity Disorder
Chapter 59: Congenital Hydrocephalus
Section K. Neurologic Manifestations of Medical Diseases – John J. Caronna
Chapter 60: Hematological Disorders
Chapter 61: Renal Disease
Chapter 62: Diabetes and Endocrine Disorders
Chapter 63: Mechanisms and Consequences of CNS Hypoxia
Chapter 64: Gastroenterologic and Hepatic Diseases and Their Effects on CNS
Chapter 65: Sarcoidosis
Section L. Sleep Disorders – Emmanuel Mignot
Chapter 66: REM Sleep Behavior Disorder
Chapter 67: The Neurobiology of Narcolepsy and Hypersomnia
Chapter 68: Restless Legs Syndrome and Periodic Leg Movement
Chapter 69: Obstructive Sleep Apnea
Chapter 70: The Neurobiology of Insomnia
Section M. Substance Abuse and Basic Toxicology – John C. M. Brust
Chapter 71: Organic Chemicals
Chapter 72: Metals
Chapter 73: Drug Addiction
Section N. Imaging the Nervous System – John C. Mazziotta
Chapter 74: Assessment of Neurobiological Diseases with Magnetic Resonance Spectroscopy
Chapter 75: Magnetic Resonance Imaging
Chapter 76: Neurovascular CT Angiography
Chapter 77: PET Imaging in Parkinson's Disease and Other Neurodegenerative Disorders
Chapter 78: Single Photon Emission Computed Tomography (SPECT)
Chapter 79: Functional Magnetic Resonance Imaging (fMRI)
Part II. Peripheral Nervous System
Section O. Peripheral Neuropathies – James Russell
Chapter 80: Diabetic and Metabolic Neuropathies
Chapter 81: Aquired Inflammatory Demyelinating and Axonal Neuropathies
Chapter 82: Toxic and Drug-Induced Neuropathies
Chapter 83: Hereditary Neuropathies
Chapter 84: Neurological Manifestations of Vasculitis
Chapter 85: Neuropathies Associated with Infections
Section P. Myopathies and neuromuscular junction disorders – Charles A. Thornton
Chapter 86: The Muscular Dystrophies
Chapter 87: Myasthenia Gravis and Myasthenic Syndromes
Chapter 88: Myopathies and Neuromuscular Junction Disorders
Chapter 89: Immunobiology of Autoimmune Inflammatory Myopathies
Section Q. Autonomic Disorders – Phillip A. Low
Chapter 90: Central Autonomic Network
Chapter 91: Autonomic Neuropathies
Chapter 92: Thermoregulation and its Disorders
Chapter 93: Control of Blood Pressure-Normal and Abnormal
Section R. Pain – Kenneth L. Casey
Chapter 94: Neoplasm-Induced Pain
Chapter 95: Pain Associated with the Autonomic Nervous System
Chapter 96: Post-Herpetic Neuralgia
Chapter 97: Central Post-Stroke Pain
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Readership: Scientists and researchers in neuroscience, neurology, neurosurgery, psychiatry, physical medicine and rehabilitation, as well as graduate students and fellows preparing for board examinations.
ISBN: 978-0-12-088592-3
ISBN10: 0-12-088592-1 Book/Hardback
Line Illustrations: 96
Measurements: 8 1/2 X 11 in
Pages: 1104
Imprint: Academic Press
Publication Date: 6 November 2006
Price: $199.95
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