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推薦指數：
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- 內容介紹
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Angiogenesis and Direct Myocardial Revascularization
Laham, Roger J. (Beth Israel-Deaconess Medical Center and Harvard Medical School, Boston, MA)
Baim, Donald S. (Brigham and Women's Hospital and Harvard Medical School, Boston, MA)
Pub. Date: May 2005
Pages: 364
Abstract:
An interdisciplinary panel of pioneers and opinion leaders review the basic, preclinical, clinical, and developmental pathways to new treatment strategies, such as therapeutic angiogenesis and myogenesis. The authors take advantage of new biological understanding, novel therapeutic targets, multiple available and well-studied therapeutic strategies, and the necessary imaging techniques to measure outcomes. Their in-depth discussions cover the identification of new therapeutic targets and pathways, the investigation of transcriptional factors, master switch molecules, cell-based approaches, chemokines, a better understanding of the effects of aging, endothelial dysfunction, and hypercholesterolemia in response to angiogenic stimuli. Highlights include examination of drug delivery problems, outcomes measure, stem therapy, high-risk interventions, development pathways, and future possibilities.
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