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Biotargets of Cancer in Current Clinical PracticeSeries: Current Clinical Pathology
Bologna, Mauro (Ed.)
2012, 2012, XVI, 563 p. 100 illus., 57 in color.
ISBN 978-1-61779-614-2
Provides the latest information on the validation status of each novel biomarker
Covers the present debate on potential clinical use of newly discovered biochemical markers and on patentability of genetic information
Chapter authors are experts on the particular cancer type
Biotargets of Cancer in Current Clinical Practice presents an updated and reasoned review of the current status of knowledge concerning the major cancer types with a special focus on the current biomarkers, genes involved and the potential future targets of innovative therapies. The volume includes for each major cancer type, a comprehensive although concise discussion of epidemiology, affirmed and innovative biomarkers for diagnosis, and descriptions of the relevant genes for prognosis and (individualized) therapy through biotarget-specific new molecular treatments, with the latest information on the validation status of each novel biomarker. Individual chapters are dedicated to the major cancer types, plus a special chapter on metastasis. The present debate on patentability of genetic information applied to diagnostics and therapeutics of cancer is also discussed
Table of contents Ch. 1- Central Nervous System Tumors
Paolo Aloisi
Francesco Martella
Davide Cerone
Giampiero Porzio
Ch. 2- Head and Neck Tumors
Keith D. Hunter
Robert Bolt
Ch. 3- Thyroid Cancer
Laura D. Locati
Angela Greco
Maria Grazia Borrello
Maria Luisa Carcangiu
Paolo Bossi
Roberta Granata
Lisa Licitra
Ch. 4- Targeted Therapies for Non-Small Cell Lung Cancer
Giulio Metro
Lucio Crinò
Ch. 5- Non-Hodgkin Lymphomas
Roberta Zappasodi
Massimo Di Nicola
Ch. 6- Leukemias
Lia Ginaldi
Massimo De Martinis
Ch. 7- Breast Cancer
Nadia Rucci
Luca Ventura
Anna Teti
Ch. 8- Esophago-Gastric Cancer
Alex M. Reece-Smith
Simon L. Parsons
Sue A. Watson
Ch. 9- Colorectal Cancer
David Church
Rachel Midgley
David Kerr
Ch. 10- Hepatocellular Carcinoma
Yasunori Minami
Masatoshi Kudo
Ch. 11- Biomarkers for Prognosis and Molecularly Targeted Therapy in Renal Cell Carcinoma
Laura S. Schmidt
Ch. 12- Bladder Cancer
Andrea Tubaro
Daniele Santini
Cosimo De Nunzio
Alice Zoccoli
Michele Iuliano
Ch. 13- Biomarkers in Prostate cancer
Mauro Bologna
Carlo Vicentini
Ch. 14- Ovarian Cancer
Jessica Wangui Oribabor
Allison Ambrosio
Cesar M. Castro
Michael J. Birrer
Ch. 15- Uterine Cancer: The Influence of Genetics and Environment on Cell Cycling Pathways in Cancer
Annekathryn Goodman
Leslie S. Bradford
Leslie A. Garrett
Ch. 16- Biotargets in Sarcomas: The Past, Present and a Look into the Future
Vivek Subbiah
Razelle Kurzrock
Ch. 17- Melanoma and other skin cancers
Kim H.T. Paraiso
Jobin K. John
Keiran S.M. Smalley
Ch. 18- Molecular pathology of cancer metastasis: suggestions for future therapy
Adriano Angelucci
Edoardo Alesse
Ch. 19- Current and future developments in cancer therapy research: miRNAs as new promising targets or tools
Marilena V. Iorio
Patrizia Casalini
Claudia Piovan
Luca Braccioli
Elda Tagliabue
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