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The Molecular Basis of Blood Disease (3/e)

-腫瘤科(血液科)

- 編號： 07216767159

- 作者：George Stamatoyannopoulos, MD

- 原價-8500 - (熱賣價)1000 - 節省 ↓88%

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- 內容介紹

The Molecular Basis of Blood Disease (3/e)
George Stamatoyannopoulos, MD, DrSci, Professor of Medicine, Department of Medicine, Division of Medical Genetics, University of Washington School of Medicine, Seattle WA
ISBN 0721676715 · Hardback · 1056 Pages · 467 Illustrations
W.B. Saunders · Published September 2000
The superb 3rd Edition covers all the groundbreaking developments that have taken place in this field since the publication of the well-received 2nd Edition. Comprehensively revised, it presents all the newest findings on the molecular bases of blood cell functions and disease mechanisms...and the impact of these discoveries on the state of medicine.
Contents

PART I: Hematopoiesis
Stem Cell Biology
Hemopoietic Growth Factors and Receptors
Transcriptional Factors that Regulate Lineage Decisions
Growth Factor Signaling

PART II: Red Cells
Hemoglobin Switching
The Thalassemias
Human Hemoglobins: Sickle Cell Hemoglobin and Other Mutants
The Erythrocyte Membrane and Cytoskeleton: Structure, Function, and Disorders
Red Blood Cell Antigenes
Molecular Basis of Iron Metabolism

PART III: Lymphopoiesis
Gene rearrangements in Lymhoic Cells
Lymphoiesis
Antigen Processing and T-Cell Effector Mechanisms

PART IV: Myelopoiesis/White Blood Cells
Integrins, Selectins, and LAD
Chemokines
Genetic Disorders of Phagocyte Function
Paroxymal Nocturnal Hemoglobins

PART V: Hemostasis
Vitamin K-Dependent Proteins
The Protein C Anticoagulant System
Regulation of Blood Coagulation by Protease Inhibitors
Hemophilia A, Hemophilia B, and von Willenbrand Disease
The Molecular Basis of Fibrin
Fibrinilysis and the Control of Hemostasis
Platelets

PART VI: Molecular Oncology
Molecular Aspects of Oncogenesis
Mechanisms of Leukemogenesis

PART VII: Viruses
The Molecular and Biological Properties of the Human Immunodeficiency Virus