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- 內容介紹
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Thrombosis and Cancer
Edited by: Anna Falanga, MD, Ajay K. Kakkar, BSc, PhD, FRCS, Gilles Lugassy, MD, Frederick R. Rickles MD
Publisher: Taylor & Francis
ISBN: 1841842877
Pub Date: 22 JAN 2004
Type: Hardback Book
It is common knowledge that thromboembolic disease is often the earliest manifestation and almost the most frequent complication of cancer. Recent studies have investigated the mechanisms by which cancer causes thrombosis and have emphasized the importance of the coagulation system in angiogenesis and tumor metastasis. Thrombosis and Cancer offers a detailed and authoritative review of the issues involved in the links between thrombosis, hemostasis, and cancer, an association long documented but still not completely understood.
This text provides comprehensive and timely coverage of the current knowledge of cancer-associated thrombosis, its pathogenesis, clinical features, prevention, and therapy. It specifically addresses the relationship between hemostatic systems and cancer, thus providing a unique and much needed focus. All of the contributors are acknowledged specialists in their fields and have experience conducting large clinical trials in oncology and thrombosis. Their discussions cover all aspects of the topic, from long-term complications to cancer surgery.
With input from specialists in a range of disciplines including hematology, pharmacology, and surgery, this thorough text will be of interest to general practitioners, internists, oncologists, hematologists, and all physicians involved in the management of cancer patients.
Contents:
1. Thrombosis and Cancer: a Short History of Trousseau's Syndrome 2. Pathogenesis of Thrombosis in Cancer 3. Platelets and Cancer 4. The Role of Clotting Factors in Tumor Metastasis: a Case for Tissue Factor 5. The Role of Fibrinolysis in Cancer 6. Tumor Angiogenesis and Blood Coagulation 7. Risk of Cancer in Patients Presenting with Venous Thromboembolism 8. Thrombotic Complications of Overt Cancer 9. Systemic Microangiopathies in the Cancer Patient 10. Thrombophilia and the Risk of Venous Thrombosis in Cancer Patients 11. Long-term Thrombotic Complications in Cancer Treated Patients: the Problem of Recurrent Venous Thromboembolism 12. Prevention of Cancer Associated Thrombosis: an Overview 13. Thromboprophylaxis in Cancer Surgery 14. Catheter Related Arm Vein Thrombosis in Patients with Cancer 15. Prevention and Treatment of Thrombosis in Cancer Patients 16. Antimalignant Properties of Antithrombotic Agents
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