力大圖書

Asthma and COPD: Basic Mechanisms and Clinical Management
by Barnes, Peter J. ; Drazen, Jeffrey M. ; Rennard, Stephen I.
0123740010 / 9780123740014
Edition 2 , 2009 , ACADEMIC PRESS INC

Key Features

Each chapter considers Asthma and COPD in side-by-side contrast and comparison – not in isolation - in the context of mechanism, triggers, assessments, therapies, and clinical management

Presents the latest and most comprehensive understandings of the mechanisms of inflammation in both Asthma and COPD

Most extensive reference to primary literature on both Asthma and COPD in one source.

Easy-to-read summaries of the latest advances alongside clear illustrations

Related Titles

Encyclopedia of Respiratory Medicine, Four-Volume Set

Description
The Second Edition of Asthma and COPD: Basic Mechanisms and Clinical Management continues to provide a unique and authoritative comparison of asthma and COPD. Written and edited by the world's leading experts, it continues to be a comprehensive review of the most recent understanding of the basic mechanisms of both conditions, specifically comparing their etiology, pathogenesis, and treatments.

Readership
Cell biologists, immunologists, pharmacologists and physicians working in pulmonary research in academia or the pharmaceutical industry

Contents
1 Definitions, Epidemiology and Genetics of Asthma and COPD 2 Epidemiology 3 Natural History 4 Genetics of Asthma and COPD 5 Pulmonary Physiology 6 Airway Pathology 7 Airway Remodeling 8 Animal Models 9 Mast Cells and Basophils 10 Dentritic Cells 11 Macrophages 12 Eosinophils 13 Lymphocytes 14 Neutrophils 15 Fibroblasts 16 Epithelial Cells 17 Mucus and Mucin-Secreting Cells 18 Airway Smooth Muscle 19 Tracheobronchial Circulation 20 Pulmonary Vessels 21 Adhesion Molecules 22 Extracellular Matrix 23 Prostanoids 24 Leukotrienes and Lipoxins 25 Reactive Oxygen Species 26 Chemokines 27 Cytokines 28 Matrix Degrading Proteinases 29 Growth Factors, 30 Nitric Oxide 31 Transcription Factors 32 Neural and Humoral Control 33 Pathophysiology of Asthma 34 Pathogenesis of COPD 35 Allergens 36 Occupational Agents 37 Infections 38 Exercise as a Stimulus 39 Atmospheric Pollutants 40 Drugs 41 Diagnosis 42 Non-invasive Assessment of Airway Inflammation 43 Imaging 44 Systemic Manifestations 45 Cardiovascular Effects 46 Allergen Avoidance 47 Smoking Cessation 48 â2-adrenoceptor Agonists 49 Anticholinergic Bronchodilators 50 Theophylline 51 Corticosteroids 52 Mediator Antagonists 53 Antibiotics 54 Long-term Oxygen Therapy 55 Immunomodulators 56 Pulmonary Vasodilators 57 Ventilator Support 58 Pulmonary Rehabilitation 59 Surgery and Other Mechanical Interventions 60 Other Therapies 61 Future Therapies 62 Health Economics 63 Management of Chronic Asthma in Adults 64 Asthma Exacerbations 65 Childhood Asthma 66 Treatment for Stable COPD 67 Acute Exacerbations of COPD 68 Education and Self-Management