Molecular Genetics of Mycobacteria
Author: Graham F. Hatfull and William R. Jacobs
Book ISBN: 1-55581-191-4
About the Book
The recent determination of the complete genome sequence of Mycobacterium tuberculosis is a landmark event that demands a reconsideration of our understanding of these organisms. This new volume provides a thorough review of all aspects of mycobacterial genetics in the context of this new genomic information and the numerous insights it brings.
Molecular Genetics of Mycobacteria begins with a historical context of the development of mycobacterial genetics, illuminating how crucial problems have been understood and overcome. The molecular genetics of the mycobacteria are then presented in four major sections: Genomes and Genetic Exchange, Gene Expression, Metabolism, and Genetic Strategies. Descriptions of the tools for performing genetic analyses are integrated with discussions on the biology that they have been employed to discover.
Appendixes at the end of the volume provide a short compilation of methods commonly used in mycobacterial genetics, a list of currently available Internet websites of use to researchers in the field, and the complete map of the M. tuberculosis genome, which serves as a reference to most of the chapters.
Molecular Genetics of Mycobacteria provides valuable resource materials and detailed reviews of major topics and suggests specific as well as fundamental questions that need to be answered.
Number of Pages: 363
Publication Date: 2000
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